Gene Therapy
Regenerative Medicine
Gene therapy for heart failure results promising
Trials of gene therapy for the treatment of advanced heart failure have produced promising results, with patients making marked improvements in several areas. ... Continue Reading
Gene therapy used to restore sight
Gene therapy has been used to restore sight in people with Leber congenital amaurosis (LCA), a rare inherited eye disease that causes severe vision loss or blindness. ... Continue Reading
Gene therapy increases survival for end-stage head and neck cancer
A gene therapy invented at The University of Texas M. D. Anderson Cancer Center is the first to succeed in a U.S. phase III clinical trial for cancer, as announced today at the American Society of Gene Therapy annual meeting in Boston. Introgen Therapeutics, Inc., reported results of its phase III trial of Advexin(r), a modified adenovirus that expresses the tumor-suppressing gene p53, for end-stage head and neck cancer. ... Continue Reading
Gene therapy shown to help men with erectile dysfunction
New research has suggested that Maxi-K gene therapy could be safe and effective for men with erectile dysfunction (ED) who have not responded to other treatments. ... Continue Reading
Gene therapy used to treat tumors
Plastic surgeons in the US have discovered a new technique of reducing the volume of cancerous tumors using gene therapy, it has been revealed. ... Continue Reading
Fighting HIV With HIV: New Gene Therapy Vector Shows Promise
Researchers at the University of Pennsylvania School of Medicine report the first clinical test of a new gene therapy based on a disabled AIDS virus carrying genetic material that inhibits HIV replication. For the first application of the new vector five subjects with chronic HIV infection who had failed to respond to at least two antiretroviral regimens were given a single infusion of their own immune cells that had been genetically modified for HIV resistance. ... Continue Reading
Genetic Hearing Loss May Be Reversible Without Gene Therapy
A large proportion of genetically caused deafness in humans may be reversible by compensating for a missing protein, based on discoveries in mice. Emory University researchers have found that in mice, increasing the amount of the protein connexin26 in the ear's cochlea compensates for an absence of another protein, connexin30. The findings come 10 years after scientists first discovered that connexin26 mutations cause much of the deafness diagnosed at birth. ... Continue Reading
Designing Cancer-Killers: A Giant Leap Forward in Cancer Treatment?
In what could be one of the biggest breakthroughs in cancer treatment, researchers from the National Cancer Institute have been able to genetically change a patient's cells to battle cancer cells. ... Continue Reading
Gene Therapy For Hereditary Lung Disease Advances
An experimental gene therapy to combat alpha-1 antitrypsin deficiency, a common hereditary disorder that causes lung and liver disease, has caused no harmful effects in patients and shows signs of being effective, University of Florida researchers say. In a clinical trial, researchers evaluated the safety of using a so-called gene vector - in this case an adeno-associated virus - to deliver a corrective gene to 12 patients who are unable to produce a protein essential for health called alpha-1 antitrypsin. ... Continue Reading
Three-in-one Virus Killer Prevents Common, Often Fatal Infections
A novel combination therapy drastically reduces the infection rate of three viruses -- and risk of death -- in transplant patients with compromised immune systems. The findings, to be reported in the Nov. 1 print edition of Nature Medicine, originate from a study conducted at Baylor College of Medicine, The Methodist Hospital, and Texas Children's Hospital. ... Continue Reading
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