Cellular Reprogramming
Biotechnology
Breakthrough in age-related decline
US scientists have succeeded in preventing age-related decline in an entire animal organ, it has been noted. ... Continue Reading
Harvard Researchers Create Computer Language That can Penetrate the "Mind" of a Cell
"Through incorporating principles of engineering, we've developed a language that can describe biology in the same way a biologist would," says Gunawardena. "The potential here is enormous. This opens the door to actually performing discovery science, to look at things like drug interactions, right on the computer." ... Continue Reading
Body clock linked to metabolism
Researchers at the University of California, Irvine, have identified a molecular link between circadian rhythms and metabolism. ... Continue Reading
Retinal cell transplants 'hold potential for treating blindness'
The transplantation of retinal cells in patients made blind by age-related macular degeneration (AMD) has proven successful in preliminary research. ... Continue Reading
Umbilical cells could improve hepatic function, study shows
A group of researchers has discovered that mononuclear blood cells taken from an umbilical cord are an effective alternative to bone marrow in hepatic diseases. ... Continue Reading
Menstrual blood may have place in regenerative medicine
Blood produced during the menstrual cycle may prove to be a useful source of stem cells for regenerative medicine, new research has revealed. ... Continue Reading
Scientists Discover Age-regulated Cellular Activities That Protect Against Protein Aggregation
By disrupting the aging process in an organism, scientists at The Scripps Research Institute and the Salk Institute for Biological Studies have discovered two mechanisms in an animal model of Alzheimer's disease that protect cells against protein aggregation that leads to damage called "proteotoxicity." Since proteotoxicity appears to cause the neurodegeneration in disorders such as Alzheimer's and Parkinson's diseases, these findings have important therapeutic implications. ... Continue Reading
Studies find general mechanism of cellular aging
Three separate studies confirm a gene that suppresses tumor cell growth also plays a key role in aging. The researchers found increasing concentration, or expression, of the gene p16INK4a in older cells; these aging cells worked poorly compared to young cells and remembered their "age" even when transferred from old mice to young mice. The cells of mice bred without the gene showed less sluggishness as the animals aged and continued to function in a manner more similar to cells from younger mice. ... Continue Reading
A Switch Between Life And Death
Cells in an embryo divide at an amazing rate to build a whole body, but this growth needs to be controlled. Controlling growth requires that some cells divide while others die; their fates are determined by signals that are passed from molecule to molecule within the cell. Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg have now discovered how one of these signaling pathways controls the life and death of cells in the fruit fly. ... Continue Reading
Lamins as youth elixir
Aging looks and feels like it is multifactorial: everything falls apart independently. But now Paola Scaffidi and Tom Misteli (National Cancer Institute, Bethesda, MD) report that multiple hallmarks of cellular aging can be reversed by eliminating one aberrant splicing product of lamin A. ... Continue Reading
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