5 Hydroxytryptophan (5-HTP)

Posted on 2005-12-30 20:01:01 in Amino Acids |

GENERAL DESCRIPTION:

The body uses 5 hydroxytryptophan, or 5-HTP to manufacture the neurotransmitter serotonin. Due to its effects upon serotonin levels, 5HT is often used as an antidepressant.

ROLE IN ANTI-AGING:

5HT’s use antidepressant effects are well-documented. Some studies have also suggested that the supplement may help to reduce the frequency and severity of migraines, however this benefit of 5HT has not been clinically proven. Recent findings have also indicated that 5HT may help to relieve the symptoms of fibromyalgia.

DEFICIENCY SYMPTOMS:

Not applicable

THERAPEUTIC DAILY AMOUNT:

100 to 200 mg of 5HT 3 times daily is the recommended initial dose; however once 5HT starts to work the dosages can usually be reduced.

MAXIMUM SAFE LEVEL: Not established

SIDE EFFECTS/CONTRAINDICATIONS:

5HT should not be used alongside the Parkinson’s drug carbidopa as it can cause skin changes similar to those that seen with the disease scleroderma. 5-HTP should not be combined with drugs that raise serotonin levels, for example SSRIs (e.g., Prozac), and other antidepressants. People with kidney disease or liver disease should consult their doctor before taking 5-HTP.

Note: See Oxitriptan (Hormones & Pharmacological Agents)


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