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Posted on Mar 27, 2013, 6 a.m.
Australian researchers reveal that by targeting a single anti-aging enzyme, SIRT1, there exists the potential to prevent age-related diseases and extend lifespans.
Submitting that: “A molecule that treats multiple age-related diseases would have a major impact on global health and economics,” David Sinclair, from the University of New South Wales (Australia), and colleagues have identified that a single anti-aging enzyme, SIRT1, which can be switched on naturally by calorie restriction and exercise, but can also be enhanced through activators (such as nutritional compounds, resveratrol – for example), thereby influencing the metabolic effects of sirtuin-activating compounds (STACs).
Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Sinclair DA, et al. “Evidence for a common mechanism of SIRT1 regulation by allosteric activators.” Science. 2013 Mar 8;339(6124):1216-9.
