eMEMBERSHIP  LOGIN

Anti-Cancer Effects of Grape Seed Extract

Posted on Dec. 24, 2013, 6 a.m. in Men's Health Cancer Functional Foods
Anti-Cancer Effects of Grape Seed Extract

Previously, a number of studies have suggested that grape seed extract may have anti-cancer effects.  Chapla Agarwal, from the University of Colorado Cancer Center (Colorado, USA), and colleagues studied the effects of the most active component of grape seed extract, B2G2, showing that the compound induces cell death (apoptosis) in prostate cancer cells while leaving healthy cells unharmed, in a laboratory model.  The team submits that: "we report B2G2 chemical synthesis at gram-quantity with equivalent biological efficacy against human [prostate cancer) cell lines and same molecular targeting profiles at key transcription factors level. The synthetic B2G2 will stimulate more research on prostate and possibly other malignancies in preclinical models and clinical translation.”

View news source…

Tyagi A, Raina K, Shrestha SP, Miller B, Thompson JA, Wempe MF, Agarwal R, Agarwal C.  “Procyanidin B2 3,3″-di-O-gallate, a Biologically Active Constituent of Grape Seed Extract, Induces Apoptosis in Human Prostate Cancer Cells Via Targeting NF-κB, Stat3, and AP1 Transcription Factors.”  Nutr Cancer. 2013 Nov 5.

  

Health Headlines MORE »

Clinical update on Ebola & The Flu from the A4M
Survival Tips from the A4M
A new blood test called the "lymphocyte genome sensitivity" (LGS) test may make it possible to detect some cancers earlier than ever before.
People genetically predisposed to develop atrial fibrillation, which dramatically raises the risk of stroke, can be identified by a blood test.
Eating a Mediterranean diet supplemented with extra-virgin olive oil or nuts may help reverse metabolic syndrome.
A loss of smell is a strong predictor of death within 5-years for older adults.
Study results suggest that drinking caffeinated or decaffeinated coffee may benefit liver health.
Infections with the intestinal superbug Clostrium difficile nearly doubled in US hospitals during 2001 to 2010.
Eating a healthy diet and generally following a healthy lifestyle may cut a woman’s risk of stroke by more than half.
Compounds found in Camelina sativa seed boost the liver's ability to clear foreign chemicals and oxidative products.