New gene therapy vector delivers therapeutic genes

Posted on 2009-09-01 21:09:19 in Cancer | Genetic Research | Genetics in Disease | Longevity and Age Management |

A report in "The Federation of American Societies for Experimental Biology Journal" describes a new gene therapy vector which can transfer DNA to a cell's nucleus far more efficiently than in the past. The development raises hopes for more effective treatment of genetic disorders and some types of cancers.

Gene therapy vectors deliver therapeutic DNA to a cell's nucleus, where it reprograms a cell to function properly. "Effective gene therapy is clearly the best way to treat heritable diseases. It's also an approach to other diseases where the environment or infection messes up our genes," states Gerald Weissmann, M.D., Editor-in-Chief of "The FASEB Journal".


The research conducted at the Nuclear Signaling Laboratory at Monash University in Victoria, Australia used proteins that mimic key functions of viruses for the packaging and transport of therapeutic DNA. "This work opens up a new era of pharmaceutical development," according to Weissmann.


News source: http://www.eurekalert.org/pub_releases/2009-08/foas-ftz083109.php

Health Headlines MORE »

The best male marathon runners over age 65, and the best female marathon runners over age 45, continue to consistently improve their performance.
UCLA-led team safely uses human embryonic stem cells to treat macular degeneration.
First-of-its-kind study reports that indoor air in offices is an important source of worker exposure to potentially toxic substances.
Twenty percent of Americans ages 18+ experienced a diagnosable mental, behavioral, or emotional disorder in 2010.
In a lab animal model, vitamin D reduced the effects of aging in the eyes and improved the vision of older animals.
For the first time ever, stem cells from umbilical cords have been converted into other types of cells, paving the way for new treatment options for spinal cord
People affected by Alzheimer's disease are more likely to have low blood levels of vitamin E, as compared to people with normal cognitive function.
Virtual reality (VR)-enhanced exercise, that combine physical exercise with computer-simulated environments and interactive videogame features, yield a greater
Providing potent protection for eyes, grapes may help to slow or help prevent the onset of age-related macular degeneration (AMD).
Review paper confirms the multiple health benefits of consuming fruits, vegetables, and whole-grain foods.
ANTI-AGING TIP OF THE DAY
Lifelong Fitness Linked to Longevity
People who stay even moderately fit as they age may live longer than those who are out-of-shape. Researchers from the University of Otago ( New Zealand) studied 4,384 middle-aged and older adults whose fitness levels were assessed via exercise treadmill tests, then whom were followed for nine years. When the team separated the participants into five groups based on fitness levels, they found that one-quarter of the least-fit men and women had died during the study period, as compared to 13% of those who were slightly more in-shape.