In that in the early stages of Alzheimer's disease, patients typically suffer a major loss of the brain connections necessary for memory and information processing, Massachusetts Institute of Technology (MIT; Massachusetts, USA) researchers have formulated a combination of three naturally occurring precursors to the fatty molecules that make up brain cell membranes (uridine, choline and the omega-3 fatty acid DHA), along with selected co-factors (including B vitamins, phosopholipids and antioxidants), in an effort to promote growth of brain synapses.  When administered to a group of 225 study participants for 12 weeks, 40% of the subjects displayed marked improvements in tests of verbal memory (as compared to 24% of controls).  Further, as noted by the team:  “Supplementation … improved memory (delayed verbal recall) in mild [Alzheimer’s Disease] patients.”