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Parkinson’s Disease Shortens Life Expectancy

Posted on Jan. 20, 2012, 6 a.m. in Parkinsons Disease Demographics

Parkinson's Disease is a brain disorder that causes tremors and difficulty with movement and walking, and most commonly affects people over the age of 50. Allison W. Willis, from Washington University (Missouri, USA), and colleagues found that of nearly 140,000 Medicare beneficiaries with Parkinson's disease diagnosed in 2002 – about half of whom were younger than 80 years –  64% had died by 2008.  This rate was similar to that seen in Medicare patients suffering myocardial infarctions and Alzheimer's Disease, and substantially higher than in those diagnosed with congestive heart failure, chronic obstructive pulmonary disease (COPD), or colorectal cancer.  The incidence of dementia was common and markedly increased the risk of death in Parkinson's Disease, whereas women, Hispanics, and individuals of Asian ancestry were at lower risk of death during the study period.  Geography did not appear to affect mortality in Parkinson's Disease patients with one exception -- those living in urban areas known to have high levels of industrial manganese pollution were at almost 20% higher risk of death than those in low-pollution areas; however, there was no difference in death rates between areas of high and low lead pollution.  Writing that: “Demographic and clinical factors impact [Parkinson's Disease] survival,” the study authors urge for: “More research is needed to understand whether environmental exposures influence [Parkinson's Disease] course or survival.”

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Allison W. Willis; Mario Schootman; Nathan Kung; Bradley A. Evanoff; Joel S. Perlmutter; Brad A. Racette.  “Predictors of Survival in Patients With Parkinson Disease.”  Arch Neurol., January 2012.

  

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ANTI-AGING TIP OF THE DAY

Tip #167 - Snooze, Don’t Lose
Too little sleep compromises many of the body’s biological processes, most notably the immune system, metabolic function, and cognitive performance (specifically, learning and memory). Researchers from Beth Israel Deaconess Medical Center (Massachusetts, USA) reported that sleep is important for the development of episodic memories, and particularly those of an emotional nature. The team studied 88 college students, and found that those subjects who slept a full evening remembered the emotional scene they were shown in far greater detail, as compared to those participants who stayed awake for 12 hours after viewing the scene.

Defying the adage that ‘you snooze, you lose,’ sleep is a vital process that helps to preserve memories. Don’t underestimate the restorative role of sleep: while the amount of sleep required is highly individualized, it is critical to get sleep of a sufficient duration that is followed by a spontaneous awakening and leaves you feeling refreshed and alert for the day.

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