Scientists develop immunization against heart disease
15 years, 8 months ago
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Posted on Jul 30, 2008, 8 p.m.
By Jeanelle Topping
Latest research findings have led to the development of a potential immunization against cardiovascular disease.
Latest research findings have led to the development of a potential immunization against cardiovascular disease.
A report published in the academic journal Atherosclerosis revealed that patients with low levels of the naturally occurring antibodies, anti-PC, have a higher risk of developing heart disease, particularly stroke, in male patients.
Independent of other known risk factors such as high blood pressure, high blood lipids, diabetes and smoking, low levels of anti-PC indicate increased risk of cardiovascular disease, almost fourfold in men who develop stroke.
Director of the study, professor Johan Frostegard, said: "Our findings suggest that anti-PC can be used as a complement to the traditional risk factors to improve diagnosis and treatment. In addition we are currently developing anti-PC as a vaccine for atherosclerosis and cardiovascular disease."
The researchers analysed data from 349 people who had suffered a heart attack or stroke in a 12-year period and 693 individuals without symptoms of cardiovascular disease.
While the causes of atherosclerosis remain unknown, experts believe the immune system may play an influential role.
