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Dietary Supplementation Cardio-Vascular Heart Health Holistic

Are Fish Oil Supplements A Good Idea? It Is Complicated

1 month, 3 weeks ago

2652  0
Posted on May 29, 2024, 2 p.m.

Article courtesy of Dr. Joel Kahn, MD, who is a Clinical Professor of Medicine at Wayne State University School of Medicine, one of the world's top cardiologists, a best-selling author, lecturer, and a leading expert in plant-based nutrition and holistic care.

At the Kahn Center, it is routine to measure an Omega Index and a large percentage of patients are very low in Omega-3. This is true of those following a vegan diet and those on an omnivore diet. Many patients are seen already taking some kind of Omega-3 supplements, usually fish or krill oil, but often algal oil.

Prior studies with high-dose prescription fish oil have reported an increase in atrial fibrillation

A new study examined relationships between taking Omega-3 supplements in a large population. The findings are "complicated". 


A prospective cohort study drawing data from the UK Biobank with entries from 2006 to 2010 and follow-up to 31 March 2021 (median follow-up of 11.9 years) was performed. 415 737 participants, aged 40-69 years, enrolled in the UK Biobank study.

Incident cases of atrial fibrillation, major adverse cardiovascular events, and death, were identified by linkage to hospital inpatient records and death registries.

The role of fish oil supplements in different progressive stages of cardiovascular diseases, from healthy status (primary stage) to atrial fibrillation (secondary stage), major adverse cardiovascular events (tertiary stage), and death (end-stage) was measured. This was NOT a randomized study.


 Among 415 737 participants free of cardiovascular diseases, 18,367 patients with atrial fibrillation, 22,636 with major adverse cardiovascular events, and 22,140 deaths during follow-up were identified.

Regular use of fish oil supplements had different roles in the transitions from healthy status to atrial fibrillation, to major adverse cardiovascular events, and then to death.

For people without cardiovascular disease, there was a 13% increase in the transition from healthy status to atrial fibrillation and a 5% increase from healthy status to stroke. 

For participants with a diagnosis of a known cardiovascular disease, regular use of fish oil supplements was beneficial for transitions from atrial fibrillation to major adverse cardiovascular events (8% lower), atrial fibrillation to myocardial infarction (15% lower), and heart failure to death (9% lower).


Regular use of fish oil supplements might be a risk factor for atrial fibrillation and stroke among the general population but could be beneficial for the progression of cardiovascular disease from atrial fibrillation to major adverse cardiovascular events, and from atrial fibrillation to death.

Further studies are needed to determine the precise mechanisms for the development and prognosis of cardiovascular disease events with regular use of fish oil supplements.

Natural sources of Omega-3 (flax, chia, and hemp seeds, walnuts, greens, algae like chlorella, and cold-water fish if selected) should be emphasized. At the Kahn Center, we will continue to check Omega-3 blood levels and emphasize higher levels in those found to be deficient. 

About the author: At his core, Dr. Joel Kahn believes that plant-based nutrition is the most powerful source of preventative medicine on the planet. Having practiced traditional cardiology since 1983, it was only after his own commitment to a plant-based vegan diet that Dr. Kahn truly began to delve into the realm of non-traditional diagnostic tools, prevention tactics, and nutrition-based recovery protocols.

As with anything you read on the internet, this article should not be construed as medical advice; please talk to your doctor or primary care provider before changing your wellness routine. This article is not intended to provide a medical diagnosis, recommendation, treatment, or endorsement. These statements have not been evaluated by the Food and Drug Administration. 

Content may be edited for style and length.

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