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Posted on Jul 29, 2013, 6 a.m.
Higher blood levels of Vitamin B6 associate with less damage to DNA, among men.
Previous studies link a higher vitamin B status with a lower risk for cancer. To elucidate the exact mechanism by which this may occur, Keisuke Kuwahara, from the National Center for Global Health and Medicine (Japan), and colleagues studied 500 subjects (293 men and 207 women), ages 21 to 66 years, employed at two municipal offices in Japan. Observing that pyridoxal – one of three forms of vitamin B6 – associated with lower urinary 8-hydroxydeoxyguanosine (8-OHdG), a marker of oxidative DNA damage, in men, the study authors write that: “The results suggest that vitamin B6 plays a role against oxidative DNA damage.”
Keisuke Kuwahara, Akiko Nanri, Ngoc Minh Pham, Kayo Kurotani, et al. “Serum vitamin B6, folate, and homocysteine concentrations and oxidative DNA damage in Japanese men and women.” Nutrition, 24 June 2013.
