Non-Profit Trusted Source of Non-Commercial Health Information
The Original Voice of the American Academy of Anti-Aging, Preventative, and Regenerative Medicine
logo logo
Genetics in Disease Neurology

Biologists determine genetics in neurological disease

10 years, 5 months ago

884  0
Posted on May 20, 2008, 8 p.m. By Jeanelle Topping

Toxic proteins created by faulty RNA have been found to contribute to a range of neurodegenerative disorders in humans.

Toxic proteins created by faulty RNA have been found to contribute to a range of neurodegenerative disorders in humans.

Researchers at the University of Pennsylvania have demonstrated that damaged RNA responsible for the toxic polyglutamine protein associated with neurological diseases such as Huntington's, assists in development of polyglutamine repeat diseases in fruit fly models.

Professor Nancy Bonini commented: "The challenge for many researchers is coupling the power of a simple genetic model, in this case the fruit fly, to the enormous problem of human neurodegenerative disease.

"By recreating in the fly various human diseases, we have found that, while the mutated protein is a toxic entity, toxicity is also going on at the RNA level to contribute to the disease."

Anti-aging physicians recognise this family of progressive neurodegenerative conditions as diseases associated with the aging process. Experts suggest that it is possible to correlate the severity of disease in a patient with their age at the onset of symptoms.ADNFCR-1506-ID-18604314-ADNFCR

Subscribe to our Newsletter

WorldHealth Videos

WorldHealth Sponsors