Centrophenoxine

Centrophenoxine is a compound of two chemicals: dimethylaminoethanol (DMAE), a compound found naturally in food, especially fish, and parachlorophenoxyacetate (pCPA), a synthetic compound similar to a group of plant hormones called "auxins". Animal studies have found that centrophenoxine is effective at removing lipofuscin (potassium age pigment) from the brain, heart, and skin. Appearances of lipofuscin in the skin are referred to as liver or age spots. Lipofuscin occurs in much higher levels in Alzheimer’s patients than in their counterparts, and some theories relate brain and memory function to the ability of potassium to enter and exit brain cells. As we age, this ability is reduced and potassium levels rise. There is also some evidence that cells undergo apotosis (programmed cell death) when a critical level of lipofuscin is present. Thus, Centrophenoxine may help to preserve these cells. Centrophenoxine can also increase production of brain RNA and aid in a patient’s oxygen consumption and carbon dioxide production.

Centrophenoxine’s possible anti-aging benefits include protection against free radical damage in the brain, increased potential lifespan, reduction and prevention of age spots on the skin, increased mental energy, improved memory and learning ability, and prevention and treatment of stroke and brain injury. Recently scientists have discovered that centrophenoxine may be useful in alleviating and preventing cognitive disturbances caused by fetal alcohol effects (FAE). A review published in the Annals of the New York Academy of Sciences in 2002 states that centrophenoxine treatment can prolong the medium life span of laboratory animals, especially when treatment is started at an early age. In some cases lifespan was increased by up to 30%, however such dramatic increases in lifespan were only seen in animals treated with centrophenoxine from the age of 6-months. Because of its low toxicity and potential positive effects in anti-aging, Centrophenoxine is considered to be an important anti-aging supplement. In France it is viewed as a superior DMAE product and is available over the counter.

Possible side effects may include nausea or mild dizziness. People with severely high blood pressure or convulsive disorders such as epilepsy should avoid Centrophenoxine.

Synonyms: Centrophenoxine Hydrochloride; Clofenoxine Hydrochloride; Clophenoxate Hydrochloride; Deanol 4 Chlorophenoxyacetate Hydrochloride; Meclofenoxane Hydrochloride.

Chemical Name: 2-Dimethylaminoethyl 4 chlorophynoxyacetate hydrochloride.

Molecular Formula: C(12)H(16)CINO(3), HCL

Molecular Weight: 294.2

Distribution: Centrophenoxine is supplied in 250mg-tablet form under the trade names Cerutil, Helfergin and Lucidri