Posted on Dec 04, 2015, 6 a.m.
Fatigue, increased irritability, and feeling demoralized, may markedly raise a healthy man or woman's risk of first-time cardiovascular disease.
The combination of fatigue, increased irritability, and feeling demoralized is medically known as vital exhaustion. Randy Cohen, from Mt. Sinai St. Luke's-Roosevelt (New York, USA), and colleagues investigated the relationship between vital exhaustion and first-time heart disease in 11 prospective studies that involved 60,610 people without heart disease. The studies had an average follow-up of 6.5 years. Data revealed that vital exhaustion associated with a 36% increase in risk for first-time cardiovascular disease, when compared to people not experiencing these three psychological factors. The study authors warn that: “[Vital exhaustion]/fatigue is a significant risk factor for incident [cardiovascular disease] in healthy subjects, comparable in potency to some of the other common psychosocial risk factors for cardiac disease.”
Jincy Thankachen, Chirag Bavishi, Randy Cohen, Alan Rozanski. “Vital Exhaustion and Incident Cardiovascular Disease: a Meta-Analysis” [Abstract #17412]. Presentation at American Heart Association's Scientific Sessions 2014, 17 Nov. 2014.