Posted on Jan 29, 2016, 6 a.m.
A simple blood sample from a patient can be used to regenerate autologous blood vessels in one week.
Vascular diseases are documented to be key components of the global burden of non-communicable diseases, as these disorders affect over 25 million individuals in westernized societies. Such patients could benefit from transplantation of tissue-engineered vascular grafts using autologous cells. Michael Olausson, from the Sahlgrenska University Hospital (Sweden) , and colleagues, have successful transplanted two pediatric patients with autologous whole peripheral blood tissue-engineered veins. The blood samples were able to regenerate autologous blood vessels in one week. The study authors submit that: “These results provide a proof of principle for the generation of transplantable vascular grafts using a simple autologous blood sample, making it clinically feasible globally.”
Olausson M, Sumitran-Holgersson S, et al. “In vivo application of tissue-engineered veins using autologous peripheral whole blood: A proof of concept study .” EBioMedicine, 22 October 2014.