Posted on Feb 10, 2010, 6 a.m.
UK researchers find that men who consume more fats, regardless of type or source, may sharply raise their risks of prostate cancer.
It is estimated that more than 500,000 new cases of prostate cancer are diagnosed worldwide every year, and the incidence of the disease is projected to rise by 1.7% over 15 years. Artitaya Lophatananon, University of Nottingham Medical School (Nottingham, United Kingdom), and colleagues assessed dietary intakes of 512 men with prostate cancer (comparing them to 838 healthy controls). The team found that those men with the highest average intakes of total fat raised their risk of prostate cancer by 153% (as compared to men with the lowest average intakes). Similar trends were observed for saturated fat, monounsaturated fats, and polyunsaturated fats. Writing that: “[T]here was a positive statistically significant association between prostate cancer risk and energy-adjusted intake of total fat and fat subtypes,” the researchers urge that: “These results potentially identify a modifiable risk factor for early-onset prostate cancer.”
Artitaya Lophatananon, Jane Archer, Douglas Easton, Richard Pocock, David Dearnaley, Michelle Guy, Zsofia Kote-Jarai, Lynne O'Brien, Rosemary A. Wilkinson, Amanda L. Hall, Emma Sawyer, Elizabeth Page, Jo-Fen Liu, Sandra Barratt, Aneela A. Rahman, The UK Genetic Prostate Cancer Study Collaborators, British Association of Urological Surgeons' Section of Oncology , Rosalind Eeles, Kenneth Muir. “Dietary fat and early-onset prostate cancer risk.” British Journal of Nutrition, online 19 Jan 2010; doi: 10.1017/S0007114509993291.