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Cancer Functional Foods

Olive Oil Compound Kills Cancer Cells

1 year, 11 months ago

3375  0
Posted on Dec 08, 2016, 6 a.m.

Oleocanthal kills cancer cells by rupturing vesicles that store cellular waste, in a cell culture model.

Extra virgin olive oil is abundant in oleocanthal, a compound for which previous studies have suggested heart-healthy benefits.  David Foster, from Hunter College (New York, USA), and colleagues employed a cell culture model to study the effects of oleocanthal on human cancer cell lines. The  team observed that “[oleocanthal] induced cell death in all cancer cells examined – as rapidly as 30 minutes after treatment …”, by inducing lysosomal membrane permeabilization to result in a  rupturing of vesicles that store cellular waste.  The study authors submit that: “targeting lysosomal membrane stability represents a novel approach to induce cancer-specific cell death.”

O LeGendre, P A S Breslin & D A Foster. “Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization (LMP).”  Molecular & Cellular Oncology, 23 Jan. 2015.

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