Posted on Dec 29, 2010, 6 a.m.
Compounds in pomegranate juice inhibit the movement of cancer cells and weaken their attraction to a chemical signal that has been shown to promote the metastasis of prostate cancer.
Previously, a 2006 study by University of California/Los Angeles (UCLA; California, USA) reported that prostate cancer patients who daily drank an eight-ounce glass of pomegranate juice demonstrated reductions in prostate-specific antigen (PSA) levels that suggested a potential slowing of cancer progression. Manuela Martins-Green, from University of California/Riverside (UCR; California, USA) now have identified components in pomegranate juice that appear to inhibit the movement of cancer cells and weaken their attraction to a chemical signal that has been shown to promote the metastasis of prostate cancer to the bone. The team plans additional testing in an in vivo model for prostate cancer to determine dose-dependent effects and side effects of the two components.
L. Wang, J. Ho, M. M. Martins-Green. “Specific Pomegranate Juice Components as Potential Inhibitors of Prostate Cancer Metastasis” (Abstract #B1037). Presented at the2010 Annual Meeting of the American Society for Cell Biology, 12 December 2010.