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Anti-Aging Research Science Alzheimer's Disease Neurology

Potential Protective Effects of Hops Compound

4 years, 3 months ago

4913  0
Posted on Mar 05, 2015, 6 a.m.

Xanthohumol, a type of flavonoid found in hops and beer, may exert protective effects against Alzheimer’s and other neurodegenerative diseases.

A flavonoid found in hops and beer, xanthohumol has been reported to ameliorate a cellular process involved in cognitive flexibility (see ).  Jianguo Fang, from Lanzhou University  (China), and colleagues conducted lab tests that recveal that xanthohumol protects neuronal cells, observing that the compound “significantly upregulates a panel of phase II cytoprotective genes as well as the corresponding gene products, such as glutathione, heme oxygenase, NAD(P)H:quinone oxidoreductase, thioredoxin, and thioredoxin reductase.”  The study authors submit that xanthohumol “might be a potential candidate for the prevention of neurodegenerative disorders.”

Yao J, Zhang B, Ge C, Peng S, Fang J.  “Xanthohumol, a Polyphenol Chalcone Present in Hops, Activating Nrf2 Enzymes To Confer Protection against Oxidative Damage in PC12 Cells.”  J Agric Food Chem. 2015 Jan 28.

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