Anti-Aging Research Science
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle
9 years, 10 months ago
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Posted on Jun 15, 2014, 3 p.m.
Circulating protein growth differentiation factor 11 (GDF11) is a rejuvenating factor for skeletal muscle [mouse]
Supplementation of systemic GDF11 levels reverses functional impairments and restores genomic integrity in aged muscle stem cells (satellite cells). Increased GDF11 levels also improve muscle structural and functional features and increase strength and endurance exercise capacity.
Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, et al. Science. 2014 May 9.
