Anti-Aging Research Science
Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention
10 years ago
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Posted on Apr 03, 2014, 3 p.m.
Oral treatment with either resveratrol or aspirin represses the accumulation of tetraploid intestinal epithelial cells [mouse model of colon cancer]
The chemopreventive action of resveratrol and aspirin involves the elimination of tetraploid cancer cell precursors.
Lissa D, Senovilla L, Rello-Varona S, Vitale I, Michaud M, Pietrocola F, Boileve A, Obrist F, Bordenave C, Garcia P, Michels J, Jemaa M, Kepp O, Castedo M, Kroemer G. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3020-5.
