Posted on Aug 28, 2012, 6 a.m.
Meta-analysis of 34 studies indicates a significant association of shift work with myocardial infarction and ischemic stroke.
A number of studies document that shift work disrupts the circadian rhythm, sleep, and work-life balance. David C. Hackam, from Western University (Canada), and colleagues conducted a meta-analysis of 34 studies involving a total of 2,011,935 adults. A pooled random-effects analysis showed that shift work was associated with a 23% higher risk of myocardial infarction (heart attack), and a 5% higher risk of ischemic stroke. Comparison of adjusted and unadjusted pooled risk ratios showed similar results. The risk persisted across different work shifts, with the exception of night-shift workers. Writing that: “Shift work is associated with vascular events,” the study authors submit that their findings “have implications for public policy and occupational medicine.”
Vyas MV, Garg AX, Iansavichus AV, Costella J, Donner A, Laugsand LE, Janszky I, Mrkobrada M, Parraga G, Hackam DG. “Shift work and vascular events: systematic review and meta-analysis.” BMJ. 2012 Jul 26;345:e4800.