eMEMBERSHIP  LOGIN

Nanoparticles In the Fight Against Cancer

Posted on Sept. 25, 2013, 6 a.m. in Nanotechnology Cancer
Nanoparticles In the Fight Against Cancer
The immune system is a complex network of cells and tissues that is integral for protecting the body against cancer.  However, most cancerous cells, avoid detection by the immune system because they so closely resemble normal cells, leaving the cancerous cells free to multiply and grow into life-threatening tumors while the body’s immune system remain unaware. Shanta Dhar, from the University of Georgia (Georgia, USA), and colleagues exposed cancer cells in a petri dish to specially designed nanoparticles 1,000 times finer than the width of a human hair. The nanoparticles invade the cell and penetrate the mitochondria—the organelles responsible for producing the energy a cell needs to grow and replicate.  The team then activated the nanoparticles inside the cancer cells by exposing them to a tissue-penetrating long wavelength laser light. Once activated, the nanoparticles disrupt the cancer cell's normal processes, eventually leading to its death.  The dead cancer cells were collected and exposed to dendritic cells, one of the core components of the human immune system, with the dendritic cells producing a high concentration of chemical signals that served to stimulate the immune response. 
View news source…
Sean Marrache, Smanla Tundup, Donald A. Harn, Shanta Dhar.  “Ex Vivo Programming of Dendritic Cells by Mitochondria-Targeted Nanoparticles to Produce Interferon-Gamma for Cancer Immunotherapy.”  ACS Nano, 2013, 7 (8), pp 7392–7402; July 30, 2013.
  

Health Headlines MORE »

About an hour of ballroom dancing 3 days a week, for 3 months, resulted in a 50% improvement in balance and fall reduction.
Sugar sweetened beverages such as sodas and juice cocktails may elevate blood pressure.
Not only did collegiate-trained swimmers recover better with chocolate milk after an exhaustive swim, they swam faster in time trials later that same day.
Regardless of speed or distance, runners tend to have lower rates of heart-disease related deaths – translating to a potential of 3 additional years of lifespan
The leaves and bark of the Voacanga africana tree may hold potential to ward off Alzheimer’s Disease.
A daily glass of beetroot juice may boost the aerobic fitness of swimmers.
USDA Forest Service calculates that trees save over 850 human lives a year and prevent 670,000 incidences of acute respiratory symptoms.
A lack of sleep may trigger errors in memory.
Daily magnesium supplementation enhances performance-boosting effects of a fitness regimen, among healthy older women.
MIT scientists create a special class of tiny gold particles can easily slip through cell membranes.