Trimethylglycine (TMG, Betaine)

Posted on Dec. 30, 2005, 8:01 p.m. in Amino Acids |

GENERAL DESCRIPTION:

TMG is a natural compound found in small quantities in some plant foods. However, humans do not need to obtain it from their diet because the body can manufacture it from other nutrients.

ROLE FOR ANTI-AGING:

Trimethylglycine is a methyl donor supplement that assists in methylation and may help protect cellular DNA from mutation. Trimethylglycine helps to keep the liver healthy by assisting the detoxification process, and animal studies suggest that the compound’s methyl group-donating properties may help to protect the liver from chemical damage. Trimethylglycine aids in the conversion of homocysteine to methionine, and thus helps to lower levels of the amino acid homocysteine, high levels of which have been linked to an increased risk of heart disease, heart attack, stroke, Alzheimer’s disease, Parkinson’s disease, and osteoporosis.

DEFICIENCY SYMPTOMS: None known

THERAPEUTIC DAILY AMOUNT:

No optimal therapeutic dosage of TMG has been established as of yet, however one manufacturer recommends dosages between 375 and 1,000 mg daily. Refer to packaging.

MAXIMUM SAFE LEVEL: Not established

SIDE EFFECTS/CONTRAINDICATIONS:

None known. People with kidney disease or liver disease should consult their doctor before taking TMG.

  

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