Non-Profit Trusted Source of Non-Commercial Health Information
The Original Voice of the American Academy of Anti-Aging, Preventative, and Regenerative Medicine
logo logo
Brain and Mental Performance

Antidepressant Therapy May Improve Cognitive Function in the Eld

21 years, 10 months ago

10011  0
Posted on Sep 25, 2002, 1 p.m. By Bill Freeman

Depressed elderly patients with cognitive impairment show an improvement in cognitive function following treatment with antidepressant drugs, however mental performance may not return to normal levels. Researchers at the university of Pittsburgh Medical Center compared cognitive function in 45 non-demented elderly patients who had major depression with that of 20 elderly controls.

Depressed elderly patients with cognitive impairment show an improvement in cognitive function following treatment with antidepressant drugs, however mental performance may not return to normal levels. Researchers at the university of Pittsburgh Medical Center compared cognitive function in 45 non-demented elderly patients who had major depression with that of 20 elderly controls. All of the depressed patients had successfully responded to a trial of nortriptyline or paroxetine for 3-months. By analyzing pre- and post-treatment scores on the Mattis Dementia Rating Scale, the scientists found that the successful treatment of depression significantly improved the cognitive function of depressed elderly patients with baseline cognitive impairment.

SOURCE/REFERENCE: American Journal of Psychiatry 2000; 157: 1949-1954

WorldHealth Videos