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Dementia Alzheimer's Disease Brain and Mental Performance Cholesterol

A Common Question: Do Statin Cholesterol Medications Cause Dementia?

2 months ago

1633  0
Posted on Mar 13, 2024, 6 p.m.

Article courtesy of Dr. Joel Kahn, MD, who is a Clinical Professor of Medicine at Wayne State University School of Medicine, one of the world's top cardiologists, a best-selling author, lecturer, and a leading expert in plant-based nutrition and holistic care.

One of the most common concerns patients share with me at the Kahn Center is their fear that lowering their cholesterol levels with "statin" medications like atorvastatin or rosuvastatin might promote dementia. 

Indeed, the potential impact of statins on cognitive decline and dementia is still debated but there is considerable data arguing for their safety. A recent review article addressed this concern with a large analysis. 


A review of studies reporting on the relationship between statin use and dementia overall, or Alzheimer's Disease (AD) specifically, was performed.

In the pooled analyses, statins were associated with a decreased risk of dementia (36 studies, 20% lower risk) and AD [21 studies (32% lower risk).

No difference was observed in the risk reduction of dementia between men and women.

Similar risks were observed for lipophilic and hydrophilic statins for both dementia and AD, while high-potency statins showed a 20% reduction of dementia risk compared with a 16% risk reduction associated with low-potency statins, suggesting a greater efficacy of the former.


There is no doubt that statin medications can cause side effects including muscle and joint issues, elevations in blood sugar, and "brain fog".  However, the major concern patients tell me about is actual dementia or AD.

These results confirm the absence of a neurocognitive risk associated with statin treatment and suggest a potentially favorable role of statins in the prevention of dementia and AD, perhaps by reducing vascular dementia and reductions in inflammation. At the Kahn Center, all patients taking statin medications combine the Rx with daily coQ10 vitamin support. 

About the author: At his core, Dr. Joel Kahn believes that plant-based nutrition is the most powerful source of preventative medicine on the planet. Having practiced traditional cardiology since 1983, it was only after his own commitment to a plant-based vegan diet that Dr. Kahn truly began to delve into the realm of non-traditional diagnostic tools, prevention tactics, and nutrition-based recovery protocols.

As with anything you read on the internet, this article should not be construed as medical advice; please talk to your doctor or primary care provider before changing your wellness routine. This article is not intended to provide a medical diagnosis, recommendation, treatment, or endorsement. These statements have not been evaluated by the Food and Drug Administration. 

Opinion Disclaimer: The views and opinions expressed in this article are those of the author and do not necessarily reflect the official policy of WHN/A4M. Any content provided by guest authors is of their own opinion and is not intended to malign any religion, ethic group, club, organization, company, individual, or anyone or anything.

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