Conditional tradeoffs between aging and organismal performance16 years, 5 months ago
Posted on Apr 26, 2003, 1 p.m.
By Bill Freeman
Alterations that extend the life span of animals and yeast typically involve decreases in metabolic rate, growth, physical activity, and/or early-life fecundity. This negative correlation between life span and the ability to assimilate and process energy, to move, grow, and reproduce, raises questions about the potential utility of life span extension.
Marden JH, Rogina B, Montooth KL, Helfand SL.
Proc Natl Acad Sci U S A 2003 Mar 18;100(6):3369-73
Department of Biology, 208 Mueller Lab, Pennsylvania State University, University Park, PA 16802, USA.
PMID: 12626742 [PubMed - indexed for MEDLINE]