Posted on Jul 01, 2013, 6 a.m.
Coenzyme Q10 may reduce mortality rates due to heart failure by half.
Coenzyme Q10 is a vitamin-like compound, found in abundant levels in the mitochondria of cells as it is a substance vital to energy production. Svend Aage Mortensen, from Copenhagen University Hospital (Denmark), and colleagues administered oral Coenzyme Q10 (100 mg, three times a day), or placebo, to 420 European and Asian subjects and followed them for a two-year period. At the end of the study term, 25% of the patients in the placebo group experienced a major adverse cardiovascular events, as compared to 14% in the group receiving CoQ10. Further, mortality and hospitalizations were lower in the supplemented group: 18 patients died in the CoQ10 group, as compared to 36 in the placebo group. The researchers observed that CoQ10 reduce the levels ofNT-proBNP, a heart failure biomarker.
Mortensen SA, Kumar A, Dolliner P, et al. “The effect of Coenzyme Q10 on morbidity and mortality in chronic heart failure. Results from the Q-SYMBIO study” [Abstract #440]. Presented at 2013 Congress of the Heart Failure Association of the European Society of Cardiology, 29 May 2013.