Non-Profit Trusted Source of Non-Commercial Health Information
The Original Voice of the American Academy of Anti-Aging, Preventative, and Regenerative Medicine
logo logo
Functional Foods Alternative Medicine Brain and Mental Performance Cognitive

Mushrooms Magnify Memory By Boosting Nerve Growth

1 year, 3 months ago

9591  0
Posted on Feb 10, 2023, 4 p.m.

Professor Frederic Meunier from the Queensland Brain Institute said the team had identified new active compounds from the mushroom, Hericium erinaceus (Lion’s Mane).

Researchers have discovered lion's mane mushrooms improve brain cell growth and memory in pre-clinical trials.

"Extracts from these so-called 'lion's mane' mushrooms have been used in traditional medicine in Asian countries for centuries, but we wanted to scientifically determine their potential effect on brain cells," Professor Meunier said.

"Pre-clinical testing found the lion's mane mushroom had a significant impact on the growth of brain cells and improving memory.

"Laboratory tests measured the neurotrophic effects of compounds isolated from Hericium erinaceus on cultured brain cells, and surprisingly we found that the active compounds promote neuron projections, extending and connecting to other neurons.

"Using super-resolution microscopy, we found the mushroom extract and its active components largely increase the size of growth cones, which are particularly important for brain cells to sense their environment and establish new connections with other neurons in the brain."

Co-author, UQ's Dr. Ramon Martinez-Marmol said the discovery had applications that could treat and protect against neurodegenerative cognitive disorders such as Alzheimer's disease.

"Our idea was to identify bioactive compounds from natural sources that could reach the brain and regulate the growth of neurons, resulting in improved memory formation," Dr. Martinez-Marmol said.

Dr. Dae Hee Lee from CNGBio Co, which has supported and collaborated on the research project, said the properties of lion's mane mushrooms had been used to treat ailments and maintain health in traditional Chinese medicine since antiquity.

"This important research is unravelling the molecular mechanism of lion's mane mushroom compounds and their effects on brain function, particularly memory," Dr. Lee said.

The study was published in the Journal of Neurochemistry.

UQ acknowledges the collaborative efforts of researchers from the Republic of Korea's Gachon University and Chungbuk National University.

As with anything you read on the internet, this article should not be construed as medical advice; please talk to your doctor or primary care provider before changing your wellness routine. This article is not intended to provide a medical diagnosis, recommendation, treatment, or endorsement.

Content may be edited for style and length.

References/Sources/Materials provided by:

https://www.uq.edu.au/news/article/2023/02/mushrooms-magnify-memory-boosting-nerve-growth-0

https://www.uq.edu.au/

http://dx.doi.org/10.1111/jnc.15767

WorldHealth Videos