Posted on Aug 08, 2018, 9 p.m.
Both genders can be experience benefits from low calorie diets which were observed to cause different metabolic effects between the sexes as suggested by a new Diabetes, Obesity, and Metabolism study conducted in Denmark.
Upwards of 2,000 overweight participants diagnosed with prediabetes participated in this study who followed a low calorie diet for 8 weeks. According to the researchers their findings showed that male participants had lost significantly more body weight than female participants had, and male participants were found to have had larger decreases in their metabolic syndrome scores, diabetes indicators, fat mass, and heart rate. Female participants were found to have had greater decreases in HDL cholesterol, hip circumference, lean body mass, and pulse pressure than that of the male participants.
Results remained the same even after adjusting for differences in weight loss; male participants appeared to have benefitted more from the low calorie diet intervention than the female participants did. Additional studies are needed to determine whether the differences between sexes will persist long term, and whether different interventions will needed to be designed depending on gender. The study’s 8 week low calorie/energy diet in individuals with prediabetes did result in the initial 10% weight loss required to achieve major metabolic improvement in this phase one of a diabetes prevention programme, explains Dr. Pia Christensen of the University of Copenhagen.
Materials provided by Wiley.
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Pia Christensen, Thomas Meinert Larsen, Margriet Westerterp-Plantenga, Ian Macdonald, J. Alfredo Martinez, Svetoslav Handjiev, Sally Poppitt, Sylvia Hansen, Christian Ritz, Arne Astrup, Laura Pastor-Sanz, Finn Sandø-Pedersen, Kirsi H. Pietiläinen, Jouko Sundvall, Mathijs Drummen, Moira A. Taylor, Santiago Navas-Carretero, Teodora Handjieva-Darlenska, Shannon Brodie, Marta P. Silvestre, Maija Huttunen-Lenz, Jennie Brand-Miller, Mikael Fogelholm, Anne Raben. Men and women respond differently to rapid weight loss: Metabolic outcomes of a multi-centre intervention study after a low-energy diet in 2500 overweight, individuals with pre-diabetes (PREVIEW). Diabetes, Obesity and Metabolism, 2018; DOI: 10.1111/dom.13466