Engineering a memory with [long-term potentiation (LTP) and long-term depression (LTD)]
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Posted on Jul 24, 2014, 2 p.m.
Optogenetics to provide the first hard evidence that long-term potentiation at brain synapses is crucial for memory formation
Strengthening of synapses by long-term potentiation is required for the formation of fearful memories, but also that weakening of the same synapses by a similar, opposing mechanism can erase the memories.
Nabavi S, Fox R, Proulx CD, Lin JY, Tsien RY, Malinow R. Nature. 2014 Jun 1.