Posted on Jan 28, 2016, 6 a.m.
Folate, abundant in green leafy vegetables such as spinach, may reduce migraine frequency.
A debilitating neurovascular disorder, migraine raises a person’s risks of cardiovascular disease and endothelial dysfunction. Lyn R. Griffiths, from Queensland University of Technology (Australia), and colleagues studied 41 women who suffered from migraine with aura, to investigate their intake of dietary folate in relation to migraine symptoms. The women were genotyped for the MTHFR C677T variant, and folate intake was tracked using a standardized food survey. Comparing folate consumption with migraine frequency, severity, and disability using linear regression, the team found a significant inverse relation between dietary folate and migraine frequency. As well, among those subjects with the MTHFR genotype, the researchers linked migraine frequency to folate consumption. The study authors report that: “The results from this study indicate that folate intake in the form of [folic acid] may influence migraine frequency in female [migraine with aura] sufferers.”
Saras Menon, Rodney A. Lea, Sarah Ingle, Michelle Sutherland, Shirley Wee, Larisa M. Haupt, Michelle Palmer, Lyn R. Griffiths. “Effects of Dietary Folate Intake on Migraine Disability and Frequency,” Headache: The Journal of Head and Face Pain. Volume 55, Issue 2, February 2015, Pages: 301–309.