Posted on Dec 17, 2013, 6 a.m.
Increased dietary intake of magnesium may reduce mortality, among people at high cardiovascular risk.
A growing body of evidence suggests that magnesium associates with heart health benefits, including to modulate blood pressure, inhibit platelet aggregation, and improve endothelial function. Spanish researchers completed a prospective study of subjects enrolled in the Prevention con Dieta Mediterranea (PREDIMED) study, in which participants at a high risk of cardiovascular risk were randomly assigned to consume a Mediterranean diet supplemented with nuts or olive oil, or a low-fat control diet. Following the subjects for five years, the team found that those with the highest average intakes of magnesium (442 mg/day) were at 59% reduced risk of cardiovascular mortality, a 37% reduction in cancer mortality, and a 34% reduction in all-cause mortality, as compared to those with the lowest average intakes of magnesium (312 mg/day). The study authors conclude that: “Dietary magnesium intake was inversely associated with mortality risk in Mediterranean individuals at high risk of [cardiovascular disease].”
Guasch-Ferre M, Bullo M, Estruch R, Corella D, Martínez-Gonzalez MA, Ros E, Salas-Salvado J, et al; on behalf of the PREDIMED Study Group. “Dietary Magnesium Intake Is Inversely Associated with Mortality in Adults at High Cardiovascular Risk.” J Nutr. 2013 Nov 20.